SCD1 Antibody (YA1163)(PBS only)

Cat. No.: HY-P81418A: Data Sheet User Guide for Antibodies
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SCD1 Antibody (YA1163) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SCD1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

SCD1 Antibody (YA1163) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SCD1.

Host

Rabbit

Molecular Weight

Predicted band size: 41 kDa;

Observed band size: 37 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

O00767

Gene ID

6319 [NCBI]

Immunogen

Recombinant protein of human SCD1

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-1:200

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates (PubMed:15907797, PubMed:18765284). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:15907797, PubMed:18765284). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids (PubMed:15610069). Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity). Plays an important role in body energy homeostasis (By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity)

Subcellular Localization：Endoplasmic reticulum membrane; Multi-pass membrane protein

Expression：
Tissue_specificity:Detected in fetal liver, lung and brain. Highly expressed in human adipose tissue, and at lower levels in human brain and lung

Subunit：May self-associate and form homodimers

Research Field

Signal Transduction

Synonyms

SCD1; FADS5; SCDOS; MSTP008

Documentation

User Guide for Antibodies (1077 KB)