SRA1 Antibody (YA5068)(PBS only)
(Synonyms: SRA1; PP7684; Steroid receptor RNA activator 1; Steroid receptor RNA activator protein; SRAP)SRA1 Antibody (YA5068) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to SRA1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:10000 |
Product Details
SRA1 Antibody (YA5068) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to SRA1.
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Host Mouse
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 24 kDa;
Purified recombinant fragment of SRA expressed in E. Coli. The exact sequence is proprietary to MCE.
affinity purified
Non-conjugated
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SRA1 is a Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis
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Subcellular Localization
Nucleus; Cytoplasm
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Expression
Tissue_specificity:Highly expressed in liver and skeletal muscle and to a lesser extent in brain. Also expressed in both normal and tumorigenic breast epithelial cell lines. Significantly up-regulated in human tumors of the breast, ovary, and uterus -
Subunit
SRA1 RNA exists in a ribonucleoprotein complex containing NCOA1.
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SwissProt ID
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Synonyms
SRA1; PP7684; Steroid receptor RNA activator 1; Steroid receptor RNA activator protein; SRAP
Documentation
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