Switch Associated Protein 70 Antibody (YA5257)

Cat. No.: HY-P85565: Data Sheet User Guide for Antibodies
FAQs
Technical Support

Switch Associated Protein 70 Antibody (YA5257) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Switch Associated Protein 70.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

Switch Associated Protein 70 Antibody (YA5257) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Switch Associated Protein 70.

Host

Mouse

Clonality

Monoclonal

분자량

Observed band size: 70 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat, Monkey

SwissProt ID

Q9UH65

Gene ID

23075 [NCBI]

Immunogen

Purified recombinant human SWAP70 protein fragments expressed in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000

Purity	affinity chromatography.	Conjugation	Non-conjugated
Modification	Unmodified

Appearance

Liquid

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity)

Subcellular Localization：Cytoplasm; Cell membrane; Nucleus; Cell projection, lamellipodium; Cytoplasm, cytoskeleton

Expression：
Tissue_specificity:It is expressed only in mature B cells, including B cells associated with mucosa-associated tissues and bronchus-associated tissues (PubMed: 10681448) . It is widely expressed. It is abundant in the spleen, and also present in high concentrations in the kidneys, lungs, and liver. It has also been found in monocytes and macrophages (PubMed: 12925760) .

Subunit：The SWAP complex consists of NPM1, NCL, PARP1 and SWAP70

Synonyms

KIAA0640; 70kDa; AV235546; FLJ39540; HSPC321; SWA 70 protein; SWAP 70; SWAP switching B-cell complex 70kDa subunit; SWAP-70; SWAP70; Switch associated protein 70; Switch-associated protein 70; SWP70_HUMAN.

각종 서류

User Guide for Antibodies (1077 KB)