TAPBPL Antibody (YA8270)

Cat. No.: HY-P88586: Data Sheet User Guide for Antibodies
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TAPBPL Antibody (YA8270) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TAPBPL.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

TAPBPL Antibody (YA8270) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TAPBPL.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 50 kDa

Species Reactivity

Human, Dog, Rat, Monkey, Mouse

SwissProt ID

Q9BX59

Immunogen

Full length human recombinant protein of human TAPBPL produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Component of the antigen processing and presentation pathway, which binds to MHC class I coupled with beta2-microglobulin/B2M. Association between TAPBPR and MHC class I occurs in the absence of a functional peptide-loading complex (PLC)

Subcellular Localization：Cell membrane,Endoplasmic reticulum membrane,Microsome membrane,Golgi apparatus membrane

Expression：Induction: By interferon gamma

Isoforms & Post-Translational Modification：Q9BX59 has 7 isomers: Q9BX59-1: 50183 Da (predicted); Q9BX59-2: 54799 Da (predicted); Q9BX59-3: 39804 Da (predicted); Q9BX59-4: 28253 Da (predicted); Q9BX59-5: 27517 Da (predicted); Q9BX59-6: 31844 Da (predicted); Q9BX59-7: 55092 Da (predicted).

Subunit：Interacts with peptide-free HLA-A*02-B2M complexes or those loaded with low affinity peptides, likely facilitating peptide exchange onto higher affinity peptides (PubMed:26869717, PubMed:35725941)

Synonyms

TAPBP-R; TAPBPR

Documentation

User Guide for Antibodies (1077 KB)