TAPBPL Antibody (YA8270)
(Synonyms: TAPBP-R; TAPBPR)TAPBPL Antibody (YA8270) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TAPBPL.
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Host:
Mouse
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Isotype:
IgG
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Application:
IHC-P, ICC/IF
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Reactivity :
Human, Dog, Rat, Monkey, Mouse
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 |
Product Details
TAPBPL Antibody (YA8270) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TAPBPL.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Dog, Rat, Monkey, Mouse
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Calculated Molecular Weight Predicted band size: 50 kDa
Full length human recombinant protein of human TAPBPL produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TAPBPL component of the antigen processing and presentation pathway, which binds to MHC class I coupled with beta2-microglobulin/B2M. Association between TAPBPR and MHC class I occurs in the absence of a functional peptide-loading complex (PLC)
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Subcellular Localization
Cell membrane,Endoplasmic reticulum membrane,Microsome membrane,Golgi apparatus membrane
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Expression
Induction: By interferon gamma
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Isoforms & Post-Translational Modification
Q9BX59 has 7 isomers: Q9BX59-1: 50183 Da (predicted); Q9BX59-2: 54799 Da (predicted); Q9BX59-3: 39804 Da (predicted); Q9BX59-4: 28253 Da (predicted); Q9BX59-5: 27517 Da (predicted); Q9BX59-6: 31844 Da (predicted); Q9BX59-7: 55092 Da (predicted).
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Subunit
Interacts with peptide-free HLA-A*02-B2M complexes or those loaded with low affinity peptides, likely facilitating peptide exchange onto higher affinity peptides (PubMed:26869717, PubMed:35725941)
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SwissProt ID
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Synonyms
TAPBP-R; TAPBPR
Documentation
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