Tropomyosin 2 Antibody (YA6927)

Cat. No.: HY-P87239: Ficha de datos User Guide for Antibodies
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Tropomyosin 2 Antibody (YA6927) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Tropomyosin 2.

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Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn
Referencias

Descripciòn

Tropomyosin 2 Antibody (YA6927) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Tropomyosin 2.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Peso molecular

Predicted band size：33 kDa;

Observed band size: 37 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P07951

Immunogen

Synthetic peptide within human Tropomyosin 2 aa 200-250 / 284.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:1000
IF-Tissue IF-Tissue: Immunofluorescence-Tissue	1:200
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100

Pureza	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 1*TBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization

Subcellular Localization：Cytoplasm, cytoskeleton

Expression：
Tissue_Specificity: Present in primary breast cancer tissue, absent from normal breast tissue

Isoforms & Post-Translational Modification：P07951 has three isomers: P07951-1: 32851 Da (predicted); P07951-2: 32990 Da (predicted); P07951-3: 28684 Da (predicted).
Phosphorylated on Ser-61 by PIK3CG

Subunit：Homodimer

Synonyms

Alpha tropomyosin antibody

Documentación

User Guide for Antibodies (1077 KB)

Referencias

[1]. /biology-dictionary/huh-5-2-cell.html [Content Brief]