Tropomyosin 2 Antibody (YA6927)
(Synonyms: Alpha tropomyosin antibody)Tropomyosin 2 Antibody (YA6927) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Tropomyosin 2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IF-Tissue, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in 1*TBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
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| Dilution Ratio | 1:1000-1:2000 | 1:1000 | 1:200 | 1:100 |
Product Details
Tropomyosin 2 Antibody (YA6927) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Tropomyosin 2.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 37 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size：33 kDa
Synthetic peptide within human Tropomyosin 2 aa 200-250 / 284.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 1*TBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Tropomyosin 2 binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization
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Subcellular Localization
Cytoplasm, cytoskeleton
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Expression
Tissue_Specificity: Present in primary breast cancer tissue, absent from normal breast tissue -
Isoforms & Post-Translational Modification
P07951 has three isomers: P07951-1: 32851 Da (predicted); P07951-2: 32990 Da (predicted); P07951-3: 28684 Da (predicted).
Phosphorylated on Ser-61 by PIK3CG -
Subunit
Homodimer
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SwissProt ID
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Synonyms
Alpha tropomyosin antibody
Documentation
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