Thioredoxin Reductase 2 Antibody (YA5251)
(Synonyms: mitochondrial; selenoprotein Z; SELZ; Thioredoxin reductase 2; Thioredoxin reductase 2 mitochondrial; thioredoxin reductase 3; thioredoxin reductase beta; Thioredoxin reductase TR3; TR 3; TR; TR beta; TR-beta; TRXR 2; TRXR2; TRXR2_HUMAN; TXNRD 2; Txnrd2.)Thioredoxin Reductase 2 Antibody (YA5251) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to Thioredoxin Reductase 2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IF-Tissue
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Reactivity :
Human
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:200-1000 | 1:50-100 |
Product Details
Thioredoxin Reductase 2 Antibody (YA5251) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to Thioredoxin Reductase 2.
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Host Rabbit
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 56 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Purified full length recombinant human TXNRD2 protein expressed in E.coli.
Endogenous
affinity chromatography.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Thioredoxin Reductase 2 is involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis. Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling[1].
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Subcellular Localization
Mitochondrion
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Expression
Tissue_specificity:It is highly expressed in the prostate, ovary, liver, testis, uterus, colon, and small intestine. Moderate expression is observed in the brain, skeletal muscle, heart, and spleen. Low expression is found in the placenta, pancreas, thymus, and peripheral blood leukocytes. High expression is observed in the kidneys according to PubMed:10608886, while low expression is observed in the kidneys according to PubMed:9923614. High expression has also been observed in the adrenal cortex (PubMed:24601690) . -
Isoforms & Post-Translational Modification
Q9NNW7 has 4 isomers: Q9NNW7-1: 56507 Da (predicted); Q9NNW7-2: 53970 Da (predicted); Q9NNW7-3: 46841 Da (predicted); Q9NNW7-4: 30291 Da (predicted).
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Subunit
Homodimer
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SwissProt ID
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Synonyms
mitochondrial; selenoprotein Z; SELZ; Thioredoxin reductase 2; Thioredoxin reductase 2 mitochondrial; thioredoxin reductase 3; thioredoxin reductase beta; Thioredoxin reductase TR3; TR 3; TR; TR beta; TR-beta; TRXR 2; TRXR2; TRXR2_HUMAN; TXNRD 2; Txnrd2.
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