Wilms Tumor Protein Antibody(YA6616)
(Synonyms: WIT 2 antibody; WT 1 antibody; AWT1 antibody; FWT1 antibody; GUD antibody; NPHS4 antibody; WAGR antibody; Wilms tumor 1 antibody; Wilms Tumor antibody; Wilms tumor protein antibody; WIT 2 antibody; WT 1 antibody; AWT1 antibody; FWT1 antibody; GUD antibody; NPHS4 antibody; WAGR antibody; Wilms tumor 1 antibody; Wilms Tumor antibody; Wilms tumor protein antibody; Wilms' tumor gene antibody; Wilms' tumor protein antibody; WIT2 antibody; WT antibody; WT1 antibody; WT1_HUMAN antibody; WT33 antibody; )Wilms Tumor Protein Antibody(YA6616) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Wilms Tumor Protein.
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Host:
Rabbit
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Isotype:
IgG
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Application:
mIHC
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Reactivity :
Mouse
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
mIHC
mIHC: Multiplex Immunohistochemical
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|---|---|
| Dilution Ratio | 1:100 |
Product Details
Wilms Tumor Protein Antibody(YA6616) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Wilms Tumor Protein.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityMouse
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Calculated Molecular Weight Predicted band size: 49 kDa
Recombinant protein within Human WT1 aa 59-269 / 449.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Wilms Tumor Protein transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA[1][2][3][4][5][6].
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Subcellular Localization
Nucleus,Nucleus, nucleolus,Cytoplasm,Nucleus speckle,Nucleus, nucleoplasm
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Expression
Tissue_Specificity: Expressed in the kidney and a subset of hematopoietic cells -
Isoforms & Post-Translational Modification
P19544 has 8 isomers: P19544-1: 49188 Da (predicted); P19544-2: 47195 Da (predicted); P19544-3: 47511 Da (predicted); P19544-4: 48872 Da (predicted); P19544-6: 34447 Da (predicted); P19544-7: 56883 Da (predicted); P19544-8: 55206 Da (predicted); P19544-9: 33086 Da (predicted).
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Subunit
Homodimer
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SwissProt ID
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Synonyms
WIT 2 antibody; WT 1 antibody; AWT1 antibody; FWT1 antibody; GUD antibody; NPHS4 antibody; WAGR antibody; Wilms tumor 1 antibody; Wilms Tumor antibody; Wilms tumor protein antibody; WIT 2 antibody; WT 1 antibody; AWT1 antibody; FWT1 antibody; GUD antibody; NPHS4 antibody; WAGR antibody; Wilms tumor 1 antibody; Wilms Tumor antibody; Wilms tumor protein antibody; Wilms' tumor gene antibody; Wilms' tumor protein antibody; WIT2 antibody; WT antibody; WT1 antibody; WT1_HUMAN antibody; WT33 antibody;
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