Antiviral agent 19
Antiviral agent 19 (Compound 3) is a selective inhibitor against Zika virus infection with an EC50 of 1.3 µM. Antiviral agent 19 has low cytotoxicity.
For research use only. We do not sell to patients.
- CAS No.: 1807887-16-6
- Formula: C29H35NO5
- Molecular Weight:477.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
EC50: 1.3 µM (Zika virus)
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| SNB-19 | CC50 |
22.7 μM
Compound: 146
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Cytotoxicity against human SNB-19 cells incubated for 24 hrs
Cytotoxicity against human SNB-19 cells incubated for 24 hrs
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[PMID: 33609889] |
| SNB-19 | CC50 |
22.7 μM
Compound: 3
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Cytotoxicity against human SNB19 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
Cytotoxicity against human SNB19 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay
|
[PMID: 31838328] |
| SNB-19 | EC50 |
1.3 μM
Compound: 3
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Antiviral activity against Zika virus PRVABC-59 infected in human SNB19 cells assessed as reduction in viral titer incubated for 24 hrs by viral titer assay
Antiviral activity against Zika virus PRVABC-59 infected in human SNB19 cells assessed as reduction in viral titer incubated for 24 hrs by viral titer assay
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[PMID: 31838328] |
| Vero | CC50 |
20.8 μM
Compound: 146
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Cytotoxicity against african green monkey Vero cells incubated for 48 hrs
Cytotoxicity against african green monkey Vero cells incubated for 48 hrs
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[PMID: 33609889] |
| Vero | CC50 |
20.8 μM
Compound: 3
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Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 31838328] |
Chemical Information
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CAS No. 1807887-16-6
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Molecular Weight 477.59
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Formula C29H35NO5
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SMILES
[H][C@]12CCC([C@H]([C@@]1(CC[C@H]([C@]2(CO)C)O)C)C/C=C3C(OC[C@@H]/3OC4=CC=CC5=C4N=CC=C5)=O)=C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antiviral agent 19 Related Classifications
HY-146417 Related Classifications
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