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Cat. No.: HY-139876

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APJ receptor agonist 3

APJ receptor agonist 3 is a potent and orally active APJ receptor agonist with an EC₅₀ value of 0.027 nM.

For research use only. We do not sell to patients.

CAS No.: 2759159-56-1
Formula: C₂₆H₂₉ClN₄O₅
Molecular Weight:512.99

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

APJ receptor agonist 3 Chemical Structure

CAS No.: 2759159-56-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

APJ receptor agonist 3 is a potent and orally active APJ receptor agonist with an EC₅₀ value of 0.027 nM.

Chemical Information

CAS No. 2759159-56-1
Molecular Weight 512.99
Formula C₂₆H₂₉ClN₄O₅
SMILES

CCCCC(N(C1=C(C=CC=C1OC)OC)C(O)=C2C(N3C[C@H](C4=CC=C(C=N4)Cl)CC3)=O)=NC2=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Pi Z, et al. Identification of 6-Hydroxypyrimidin-4(1H)-one-3-carboxamides as Potent and Orally Active APJ Receptor Agonists. ACS Med Chem Lett. 2021 Oct 22;12(11):1766-1772. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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