1. Apoptosis
  2. Apoptosis
  3. Apolizumab

Apolizumab (Hu1D10) is a humanized monoclonal anti-Human leukocyte antigen-DR beta-chain antibody. Apolizumab can mediate apoptosis of chronic lymphocytic leukemia (CLL) cells in vitro.

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Apolizumab Chemical Structure

Apolizumab Chemical Structure

CAS No. : 267227-08-7

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Description

Apolizumab (Hu1D10) is a humanized monoclonal anti-Human leukocyte antigen-DR beta-chain antibody. Apolizumab can mediate apoptosis of chronic lymphocytic leukemia (CLL) cells in vitro[1][2].

In Vitro

Apolizumab can induce ADCC and CMC based on expression of target antigen[2].
Apolizumab alter cell membrane polarization and permeability but may not induce apoptosis directly[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
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[Apolizumab]

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Apolizumab Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Apolizumab
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HY-P99442
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