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Cat. No.: HY-N20697

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Ariestatin A

Ariestatin A is an antibacterial agent that exhibits significant inhibitory effects against a variety of Gram-positive bacteria, including Bacillus subtilis, Staphylococcus aureus, and methicillin-resistant Staphylococcus aureus. Ariestatin A is extracted from the fungus Austroacremonium gemini MST-FP2131, and it is a glycosylated hybrid polyketide with a saturated C15 alkyl side chain. Ariestatin A shows no cytotoxic activity against mammalian cells and does not affect the growth of Saccharomyces cerevisiae. Ariestatin A can be used for bacterial infections caused by the aforementioned Gram-positive bacteria.

For research use only. We do not sell to patients.

Formula: C₃₄H₄₈O₁₂
Molecular Weight:648.74

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Ariestatin A Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Ariestatin A (96 h) potently inhibits the growth of Bacillus subtilis (MIC=1.6 μg/mL), Staphylococcus aureus (MIC=3.1 μg/mL), and methicillin-resistant S. aureus (MIC= 6.3 μg/mL), while displaying no antifungal activity against Saccharomyces cerevisiae and no cytotoxicity against mouse myeloma NS-1 or neonatal foreskin fibroblast cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 648.74
Formula C₃₄H₄₈O₁₂
SMILES

OC1=CC(O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)=CC(CCCCCCCCCCCCC)=C1C(OC3=CC(C)=C(C(O)=O)C(O)=C3)=O
Structure Classification
- Phenols
- Polyphenols
Initial Source
- Microorganisms
Austroacremonium gemini
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Sbaraini N, et al. The aquastatin biosynthetic gene cluster encodes a versatile polyketide synthase capable of synthesising heteromeric depsides with diverse alkyl side chains. Chemical science. 2024 Oct 24;15(45):18872-80. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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