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Art. -Nr.: HY-169249

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Aekatperone

Name: Aekatperone
Brand: MedChemExpress
SKU: HY-169249
Availability: PreOrder

(Synonyms: Z1620764636)

Aekatperone is a reversible K_ATP channel inhibitor, with an IC₅₀ of 9 μM. Aekatperone can be used for the research of congenital hyperinsulinism (CHI).

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₂₀H₂₅N₅O₂S
Molecular Weight:399.51

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Aekatperone Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

Aekatperone is a reversible K_ATP channel inhibitor, with an IC₅₀ of 9 μM. Aekatperone can be used for the research of congenital hyperinsulinism (CHI)^[1].

Chemical Information

Molecular Weight 399.51
Formel C₂₀H₂₅N₅O₂S
SMILES

O=S(C(C=CC=C1)=C1CN2C=CN=C2)(NC3=NNC(CC4CCCCC4)=C3)=O
Synonyms

Z1620764636
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Protokoll

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. ElSheikh A, et al. AI-Based Discovery and CryoEM Structural Elucidation of a KATP Channel Pharmacochaperone. bioRxiv [Preprint]. 2024 Sep 5:2024.09.05.611490. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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