Bromodichloromethane
Bromodichloromethane (Dichlorobromomethane) is a type of trihalomethane, commonly found in chlorinated drinking water for disinfection, and is a disinfection by-product. The bromination of bromodichloromethane can cause the formation of mutagenic intermediates through the transformation mediated by glutathione S-transferase (GST). Bromodichloromethane inhibits the differentiation of human placental trophoblast cells and reduces the secretion of chorionic gonadotropin (CG). Bromodichloromethane has potential reproductive toxicity and carcinogenicity.
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- CAS. Nr.: 75-27-4
- Formel: CHBrCl2
- Molecular Weight:163.83
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 75-27-4
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Molecular Weight 163.83
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Formel CHBrCl2
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SMILES
ClC(Br)Cl
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Synonyms
Dichlorobromomethane
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Pegram RA, et al. Glutathione S-transferase-mediated mutagenicity of trihalomethanes in Salmonella typhimurium: contrasting results with bromodichloromethane off chloroform. Toxicol Appl Pharmacol. 1997 May;144(1):183-8. [Content Brief]
[2]. Chen J, et al. Bromodichloromethane inhibits human placental trophoblast differentiation. Toxicol Sci. 2004 Mar;78(1):166-74. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)