EB-0176
EB-0176 is a potent inhibitor of ER α-glucosidases (α-Glu) Iand II with IC50s of 0.6439 and 0.0011 μM, respectively. EB-0176 is a N-substituted derivative of valiolamine with broad-spectrum antiviral. EB-0176 has the potential for the reseach of broad-spectrum agent against the existing and emerging viruses.
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- CAS. Nr.: 2758314-64-4
- Formel: C23H33N5O7
- Molecular Weight:491.54
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Glucosidase[1]
Endoplasmic Reticulum α-Glucosidases I and II inhibitor[1]
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Cell Line
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Type | Value | Description | References |
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| Vero | CC50 |
761.5 μM
Compound: EB-0176
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Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 3 to 5 days by Cell titer-glo luminescent assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 3 to 5 days by Cell titer-glo luminescent assay
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[PMID: 34870992] |
Chemical Information
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CAS. Nr. 2758314-64-4
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Molecular Weight 491.54
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Formel C23H33N5O7
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SMILES
O[C@@H]1[C@H]([C@@H]([C@](O)(C[C@@H]1NCCCCCCNC2=C(C=C(C=C2)C3=NC=CC=N3)[N+]([O-])=O)CO)O)O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
EB-0176 Related Classifications
HY-145275 Related Classifications
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