PBLD - phenazine biosynthesis like protein domain containing Gene

Also Known as MAWBP; MAWDBP; HEL-S-306

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 64081

About PBLD

Cytogenetic location: 10q21.3 Genomic coordinates (GRCh38): 10:68,282,660-68,332,928 (from NCBI)

This gene has 7 transcripts (splice variants) and 223 orthologues. Biased expression in kidney (RPKM 94.0), duodenum (RPKM 62.5) and 5 other tissues.

Summary

Enables identical protein binding activity. Involved in maintenance of gastrointestinal epithelium; negative regulation of SMAD protein signal transduction; and negative regulation of transforming growth factor beta receptor signaling pathway. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PBLD Products (2)

mRNA Protein Name
NM_001033083.2 NP_001028255.1 phenazine biosynthesis-like domain-containing protein isoform b
NM_022129.4 NP_071412.2 phenazine biosynthesis-like domain-containing protein isoform a

PBLD Protein Structure

PhzC-PhzF

PhzC-PhzF: Phenazine biosynthesis-like protein (9 - 284)

  • 0
  • 100
  • 200
  • 288 a.a.
Protein Preferred Names Protein Names

phenazine biosynthesis-like domain-containing protein

  • MAWD-binding protein

PBLD Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
PBLD P30039 CCDC184 Homo sapiens Q52MB2
Y2H Prey Pooling
32296183
Intra
PBLD P30039 CCDC184 Homo sapiens Q52MB2
Validated Y2H
32296183
Intra
PBLD P30039 CCDC184 Homo sapiens Q52MB2
Y2H Array
25416956
Intra
PBLD P30039 CCDC184 Homo sapiens Q52MB2
Y2H Array
32296183
Intra
PBLD P30039 BEND7 Homo sapiens Q8N7W2-2
Y2H Array
32296183
Intra
PBLD P30039 BEND7 Homo sapiens Q8N7W2-2
Validated Y2H
32296183
Intra
PBLD P30039 BEND7 Homo sapiens Q8N7W2-2
Y2H Prey Pooling
32296183
Intra
PBLD P30039 AMOT Homo sapiens A2BDD9
Y2H Array
32296183
Intra
PBLD P30039 AMOT Homo sapiens A2BDD9
Y2H Prey Pooling
32296183
Intra
PBLD P30039 VAC14 Homo sapiens Q08AM6
Validated Y2H
32296183
Intra
PBLD P30039 VAC14 Homo sapiens Q08AM6
Y2H Prey Pooling
32296183
Intra
PBLD P30039 VAC14 Homo sapiens Q08AM6
Y2H Array
32296183
Intra
PBLD P30039 EFHC2 Homo sapiens Q5JST6
Y2H Prey Pooling
25416956
Intra
PBLD P30039 EFHC2 Homo sapiens Q5JST6
Validated Y2H
25416956
Intra
PBLD P30039 EFHC2 Homo sapiens Q5JST6
Y2H Prey Pooling
32296183
Intra
PBLD P30039 EFHC2 Homo sapiens Q5JST6
Validated Y2H
32296183
Intra
PBLD P30039 EFHC2 Homo sapiens Q5JST6
Y2H Array
32296183
Intra
PBLD P30039 TRIP13 Homo sapiens Q15645
Validated Y2H
25416956
Intra
PBLD P30039 TRIP13 Homo sapiens Q15645
Y2H Array
25416956
Intra
PBLD P30039 ZRANB1 Homo sapiens Q9UGI0
Anti Tag CoIP
33961781
Intra
PBLD P30039 ZRANB1 Homo sapiens Q9UGI0
Anti Tag CoIP
28514442
Intra
PBLD P30039 ZRANB1 Homo sapiens Q9UGI0
Validated Y2H
32296183
Intra
PBLD P30039 ZRANB1 Homo sapiens Q9UGI0
Y2H Prey Pooling
32296183
Intra
PBLD P30039 ZRANB1 Homo sapiens Q9UGI0
Y2H Array
32296183
Intra
PBLD P30039 TCF4 Homo sapiens P15884
Y2H Array
25416956
Intra
PBLD P30039 LNX1 Homo sapiens Q8TBB1
Y2H Array
25416956
Intra
PBLD P30039 GRAP2 Homo sapiens O75791
Y2H Prey Pooling
32296183
Intra
PBLD P30039 GRAP2 Homo sapiens O75791
Y2H Array
32296183
Intra
PBLD P30039 PBLD Homo sapiens P30039
Validated Y2H
32296183
Intra
PBLD P30039 PBLD Homo sapiens P30039
Y2H Array
25416956
Intra
PBLD P30039 PBLD Homo sapiens P30039
Y2H Array
32296183
Intra
PBLD P30039 PBLD Homo sapiens P30039
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant PBLD Proteins

Art. -Nr. Produktname Accession Reinheit
HY-P71144 PBLD Protein, Human (His) P30039-1(M1-A288) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Retinal Arteries, Tortuosity Of

  • Retinal Arterial Tortuosity

  • Retinal Hemorrhage With Vascular Tortuosity

  • RATOR

  • Tortuosity Of Retinal Arteries

  • Retinal Arteriolar Tortuosity

  • Familial Isolated Retinal Arterial Tortuosity

  • Tortuosity, Arteries, Retinal
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-N3561 Cedrelone Inducer / Unkown
HY-RS10104 PBLD Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus PBLD MGD MGI:1915621
Rattus norvegicus PBLD RGD RGD:621263
Felis catus PBLD VGNC VGNC:64055
Macaca mulatta PBLD VGNC VGNC:75669
Bos taurus PBLD VGNC VGNC:32605
Canis familiaris PBLD VGNC VGNC:44284
Others PBLD NCBI