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Art. -Nr.: HY-116135

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R24

R24 is a type of flavonoid derivative. R24 exhibits strong anti-angiogenic and anti-proliferative effects. R24 induces cell apoptosis and promotes the production of reactive oxygen species (ROS). R24 can be used for the study of cancers such as lung cancer and colorectal cancer.

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CAS. Nr.: 151417-66-2
Formel: C₁₉H₁₆O₆
Molecular Weight:340.33

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

R24 Chemical Structure

CAS. Nr.: 151417-66-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
- In Vivo
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

R24 inhibits A549, AsPC-1, HCT-116, and PC-3 cell lines with IC₅₀s of 3.44, 3.59, 1.22, and 11.83 μM, respectively^[1].
R24 (2.5 μM, 48 h) induces A549 cells apoptosis and increases cell accumulation in the sub-G1 phase^[1].
R24 (2.5-10 μM, 30 min) promotes intracellular ROS production in a dose-dependent manner in A549 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis Analysis^[1]

Cell Line:

A549 cells
Concentration:

2.5 μM
Incubation Time:

48 h
Result:

Increased early and late apoptosis rate.

Cell Cycle Analysis^[1]

Cell Line:

A549 cells
Concentration:

2.5 μM
Incubation Time:

48 h
Result:

Increased cell accumulation in the sub-G1 phase.

In Vivo

R24 (60 μg/egg, 48 h) disrupts angiogenesis in chicken embryos^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 151417-66-2
Molecular Weight 340.33
Formel C₁₉H₁₆O₆
SMILES

O=C1C2=CC=C(C=C2OC3=CC(OCC4OC4)=CC=C31)OCC5OC5
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Zhang M, et al. A new flavonoid regulates angiogenesis and reactive oxygen species production. Adv Exp Med Biol. 2014;812:149-155. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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