Rabdoternin E
Rabdoternin E is a potential anti-inflammatory and antitumor agent. 2α-Acetoxy-14,15-cyclopimara-7β,16-diol only inhibits nitric oxide (NO) production in lipopolysaccharide (LPS)-induced RAW264.7 macrophages (IC50=2.3 μM) and exhibits cytotoxicity against human tumor cells such as HL-60 and SW-480 (IC50 values ??of 2.6 μM and 4.1 μM, respectively). Rabdoternin E is an ent-kaurane-type diterpenoid compound that can be naturally extracted from the 70% acetone aqueous extract of the aerial parts of Isodon rosthornii (Diels) Hara (a plant of the Lamiaceae family, Isodon genus).
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- CAS. Nr.: 155969-82-7
- Formel: C21H30O7
- Molecular Weight:394.46
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Chemical Information
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CAS. Nr. 155969-82-7
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Molecular Weight 394.46
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Formel C21H30O7
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SMILES
O[C@]12[C@]34[C@](CC[C@](C(C4=O)=C)([H])C3O)([H])[C@@]5([C@@H](O2)OC)C(C(C)(CC[C@H]5O)C)([H])[C@@H]1O
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Rabdoternin E Related Classifications
HY-N16817 Related Classifications
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