Tiancimycin A
Tiancimycin A (TNM A) is an anticancer agent. Tiancimycin A induces rapid DNA damage, cell cycle arrest, and apoptosis. Tiancimycin A can be isolated from Streptomyces sp. CB03234.
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- CAS. Nr.: 1965327-09-6
- Formel: C27H19NO8
- Molecular Weight:485.44
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 1965327-09-6
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Molecular Weight 485.44
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Formel C27H19NO8
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SMILES
C[C@H]([C@@]12[C@]3(O2)C4=CC(O)=C(C(C5=CC=C6OC)=O)C(C(C5=C6O)=O)=C4N[C@@]1([H])C#CC=CC#C[C@H]3O)O
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Synonyms
TNM A
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Structure Classification
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Initial Source
Streptomyces sp.
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Feng X, et al. Liposome-Encapsulated Tiancimycin A Is Active against Melanoma and Metastatic Breast Tumors: The Effect of cRGD Modification of the Liposomal Carrier and Tiancimycin A Dose on Drug Activity and Toxicity. Mol Pharm. 2022 Apr 4;19(4):1078-1090. [Content Brief]
[2]. Liu L,et al. Ribosome engineering and fermentation optimization leads to overproduction of tiancimycin A, a new enediyne natural product from Streptomyces sp. CB03234. J Ind Microbiol Biotechnol. 2018 Mar;45(3):141-151. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Tiancimycin A Related Classifications
HY-N15670 Related Classifications
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