YIGSRC
YIGSRC is a laminin-mimetic peptide. YIGSRC supports endothelial cell adhesion and tube formation. YIGSRC contains a cysteine residue for chemical modification to hydrogels via thiol-ene reaction. YIGSRC can be chemically modified onto hydrogels to improve in vitro vascularization.
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- CAS. Nr.: 123946-91-8
- Formel: C29H47N9O9S
- Molecular Weight:697.80
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
In Vitro
YIGSRC peptide (1.25 mM; 24 h) enhances spreading and tubular structure formation of human umbilical vein endothelial cells in non-porous hydrogels, increasing the HUVEC area relative to unmodified hydrogels[1].
YIGSRC peptide (1.25 mM; 24 h) causes a minor, statistically significant increase in the area of human umbilical vein endothelial cells in microfiber network hydrogels, though the hydrogel's porous microstructure has a more dominant effect on cellular spreading[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS. Nr. 123946-91-8
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Molecular Weight 697.80
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Formel C29H47N9O9S
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SMILES
O=C(N[C@@H]([C@@H](C)CC)C(NCC(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CS)C(O)=O)=O)=O)=O)=O)[C@H](CC1=CC=C(C=C1)O)N
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Sequence
Tyr-Ile-Gly-Ser-Arg-Cys
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Sequence Shortening
YIGSRC
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)