ATG16L1 stabilizer-1
ATG16L1 stabilizer-1 (compound A3B) is an FKBP12-independent ATG16L1 stabilizer that promotes cellular Autophagy. ATG16L1 stabilizer-1 inhibits ATG16L1 with an EC50 of 12.1 μM in the presence or absence of FKBP12. ATG16L1 stabilizer-1 alone induces GFP-LC3 puncta formation to a small extent with an EC50 of 12.0 μM.
For research use only. We do not sell to patients.
- Formula: C45H62N14O5S
- Molecular Weight:911.13
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 911.13
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Formula C45H62N14O5S
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SMILES
O=C(C(C(C)(C)CC)=O)N1CCCC[C@@]1([H])C(N[C@@](CCC2=CC=C(OC)C=C2)([H])C(N3[C@@H]4C[C@H](NC5=NC(N6CCN7C(C6)=NC=N7)=NC(NCCC8=C(C)N=C(N)S8)=N5)C[C@H]3CC4)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)