ATG5 PPI-IN-5
ATG5 PPI-IN-5 is a Autophagy-Related ATG5 protein-protein interaction inhibitor and autophagy inhibitor. The IC50 values of ATG5 PPI-IN-5 for the interactions of ATG5-ATG16L1 and ATG5-TECAIR are >33 μM.
For research use only. We do not sell to patients.
- CAS No.: 2841473-97-8
- Formula: C29H21NO4
- Molecular Weight:447.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
ATG5 PPI-IN-5 (compound 17h) (>33 μM) does not inhibit the ATG5-ATG16L1 or ATG5-TECAIR protein-protein interactions, with IC50 values >33 μM for both interactions[1].
ATG5 PPI-IN-5 (20 μM; 6 h) results in an autophagy incidence of 20.64% in COS-7 cells when treated at 20 μM for 6 h[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:COS-7 cells
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Concentration:20 μM
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Incubation Time:6 h
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Result:Resulted in an autophagy incidence of 20.64%.
Chemical Information
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CAS No. 2841473-97-8
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Molecular Weight 447.48
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Formula C29H21NO4
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SMILES
O=C(N(C(C1=CC=CC=C1)=C/2)CC3=CC=C(C=C3)C(O)=O)C2=C\C4=CC=C(C5=CC=CC=C5)O4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ATG5 PPI-IN-5 Related Classifications
HY-183827 Related Classifications
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