ATG5/TECAIR-IN-3
ATG5/TECAIR-IN-3 is a ATG5 inhibitor with autophagy inhibitory activity. ATG5/TECAIR-IN-3 selectively inhibits the ATG5-TECAIR interaction (IC50=31.24 μM) and shows no activity against the ATG5-ATG16L1 interaction.
For research use only. We do not sell to patients.
- CAS No.: 2841473-79-6
- Formula: C23H16N2O6
- Molecular Weight:416.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
ATG5-TECAIR-IN-2 (compound 12c) inhibits the ATG5-TECAIR interaction with an IC50 of 31.24 μM, with no obvious activity against the ATG5-ATG16L1 interaction[1].
ATG5-TECAIR-IN-2 (20 μM; 6 h) reduces autophagy incidence in COS-7 cells to 3.29%, indicating autophagy inhibition[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:COS-7 cells
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Concentration:20 μM
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Incubation Time:6 h
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Result:Reduced autophagy incidence in COS-7 cells to 3.29%.
Chemical Information
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CAS No. 2841473-79-6
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Molecular Weight 416.38
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Formula C23H16N2O6
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SMILES
O=C(O)CN1C(/C(C=C1C2=CC=CC=C2)=C/C3=CC=C(C4=CC=C([N+]([O-])=O)C=C4)O3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ATG5/TECAIR-IN-3 Related Classifications
HY-183829 Related Classifications
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