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Cat. No.: HY-106258

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Atilmotin

(Synonyms: OHM 11638; BAX-ACC 1638; MOT 288)

OHM 11638 (Atilmotin), an analogue of the (1-14) fragment of porcine motilin, is a motilin receptor agonist with a pK_d of 8.94 for the motilin receptor. OHM 11638 affects esophageal, lower esophageal sphincter (LES), and gastric motility. OHM 11638 increases LES and gastric pressures, OHM 11638 can be used as prokinetic agents.

For research use only. We do not sell to patients.

CAS No.: 533927-56-9
Formula: C₈₆H₁₃₅N₂₀O₁₉⁺
Molecular Weight:1753.11

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Atilmotin Chemical Structure

CAS No.: 533927-56-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

IC₅₀ & Target

pKd: 8.94 (Motilin Receptor)^[1]

Chemical Information

CAS No. 533927-56-9
Molecular Weight 1753.11
Formula C₈₆H₁₃₅N₂₀O₁₉⁺
Synonyms

OHM 11638; BAX-ACC 1638; MOT 288
Sequence

{Phe(Me3)}-Val-Pro-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Leu-Lys
Sequence Shortening

{Phe(Me3)}-VPIFTYGELQRLK
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (259 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Peeters T L. Motilin and the Discovery and Development of Motilinomimetics. Old Herborn University Seminar Monograph. INSTITUTE FOR MICROBIOLOGY AND BIOCHEMISTRY, 1997, 9: 77-87.

[2]. Korimilli A, Parkman HP. Effect of atilmotin, a motilin receptor agonist, on esophageal, lower esophageal sphincter, and gastric pressures. Dig Dis Sci. 2010 Feb;55(2):300-6. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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