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Cat. No.: HY-P12351

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AYNVTQAFGR

AYNVTQAFGR is a SARS-CoV-2 nucleocapsid protein peptide. AYNVTQAFGR is not significantly affected by known SARS-CoV-2 mutations. AYNVTQAFGR serves as a target for SISCAPA immunocapture and AEMS quantification in nasopharyngeal swabs. AYNVTQAFGR acts as a surrogate marker for SARS-CoV-2 nucleocapsid protein in mass spectrometry-based targeted assays. AYNVTQAFGR is useful for COVID-19 research.

For research use only. We do not sell to patients.

CAS No.: 2438158-37-1
Formula: C₅₀H₇₅N₁₅O₁₅
Molecular Weight:1126.22

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Custom Peptide Synthesis

AYNVTQAFGR Chemical Structure

CAS No.: 2438158-37-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
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Biological Activity

Description

In Vitro

AYNVTQAFGR and QQTVTLLPAADLDDFSK are the optimal nucleocapsid-derived peptides for targeted assay development^[3].
Incorporation of FAIMS into the assay workflow significantly improves signal-to-noise ratio and enables detection of AYNVTQAFGR peptide in low viral load nasopharyngeal swab samples^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS No. 2438158-37-1
Molecular Weight 1126.22
Formula C₅₀H₇₅N₁₅O₁₅
Sequence

Ala-Tyr-Asn-Val-Thr-Gln-Ala-Phe-Gly-Arg
Sequence Shortening

AYNVTQAFGR
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Hober A, et al. Rapid and sensitive detection of SARS-CoV-2 infection using quantitative peptide enrichment LC-MS analysis. eLife. 2021 Nov 08;10:e70843.

[2]. Van Puyvelde B, et al. Acoustic ejection mass spectrometry empowers ultra-fast protein biomarker quantification. Nature communications. 2024 Jun 15;15(1):5114.

[3]. Renuse S, et al. A mass spectrometry-based targeted assay for detection of SARS-CoV-2 antigen from clinical specimens. EBioMedicine. 2021 Jul;69:103465.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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