Azintuxizumab vedotin
Based on 1 Customer Validation
Azintuxizumab vedotin (ABBV-838) is an antibody–drug conjugate (ADC) targeting a unique epitope of CD2 subset 1, a cell-surface glycoprotein expressed on multiple myeloma cells.
For research use only. We do not sell to patients.
- Purity : 98.00%
- CAS No.: 1826819-58-2
- Molecular Weight:146.036 kDa
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Storage:
-80°C, protect from light
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
IC50 & Target
SLAMF7/CS1
In Vitro
Azintuxizumab vedotin (ABBV-838) is an ADC comprising a humanized recombinant immunoglobulin G1κ directed against a unique epitope of CD2 subset 1 (CS1, also known as SLAMF7) conjugated to the cytotoxic monomethyl auristatin E (MMAE) through a valine-citrulline linker[1].
Azintuxizumab vedotin shows potent cytotoxic activity against cancer cells that expressed CS1[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Gene ID
Format
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Human IgG1 kappa
Chemical Information
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CAS No. 1826819-58-2
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Appearance Liquid
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Molecular Weight 146.036 kDa
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Color Colorless to light yellow
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SMILES
[Azintuxizumab vedotin]
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Synonyms
ABBV-838
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Shipping
Shipping with dry ice.
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Storage
-80°C, protect from light
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Azintuxizumab vedotin Related Classifications
HY-P99454 Related Classifications
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