BACE1-IN-4
BACE1-IN-4 is a potent and highly selective BACE1 inhibitor, with an IC50 of 3.8 nM and a Ki of 1.9 nM, more selective at BACE1 over BACE2. Anti-Alzheimer’s disease.
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- No. CAS: 2361157-92-6
- Fòrmula: C21H23F2N5O4S2
- Peso molecular:511.57
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
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HY-16759
VerubecestatBACE1/2 Inhibitor -
HY-13240
LY2886721BACE1 Inhibitor -
HY-100740
LanabecestatBACE1 Inhibitor -
HY-10472
LY2811376BACE1 Inhibitor -
HY-10133
β-Secretase Inhibitor IVBACE-1 Inhibitor -
HY-13438
AZD3839 free baseBACE1 Iinhibitor -
HY-100182
BACE1-IN-1BACE1/2 Inhibitor -
HY-109055
ElenbecestatBACE-1 Inhibitor -
HY-112157
PF-06751979BACE1 Inhibitor -
HY-16759R
Verubecestat (Standard)BACE1/2 Inhibitor -
HY-10472R
LY2811376 (Standard)Reference Standard -
HY-100182R
BACE1-IN-1 (Standard)Reference Standard
Actividad biológica
Descripciòn
IC50 & Target
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BACE1 |
In Vitro
BACE1-IN-4 (Compound 22) is a potent and highly selective BACE1 inhibitor, with an IC50 of 3.8 nM and a Ki of 1.9 nM, more selective at BACE1 over BACE2 (IC50, 2090 nM; Ki, 1740 nM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2361157-92-6
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Peso molecular 511.57
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Fòrmula C21H23F2N5O4S2
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SMILES
NC1=N[C@@](C2=CC(NC(C3=NC=C(OCF)N=C3)=O)=CC=C2F)(C)C4(CCS(CC4)(=O)=O)CS1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BACE1-IN-4 Related Classifications
HY-128594 Related Classifications
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