Baloxavir marboxil-d1
Baloxavir marboxil-d1 (S-033188-d1) is the d1-labeled Baloxavir marboxil (HY-109025). Baloxavir marboxil (S-033188) is a selective inhibitor of influenza cap-dependent endonuclease. Baloxavir marboxil, a potent antiviral agent, shows activity against influenza A and B virus.
For research use only. We do not sell to patients.
- CAS No.: 2246959-10-2
- Formula: C27H22DF2N3O7S
- Molecular Weight:572.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2246959-10-2
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Unlabeled CAS 1985606-14-1
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Molecular Weight 572.56
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Formula C27H22DF2N3O7S
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SMILES
COC(OCOC1=C2N(C=CC1=O)N([C@@]3([2H])C4=CC=C(F)C(F)=C4CSC5=CC=CC=C53)[C@@]6([H])N(CCOC6)C2=O)=O
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Synonyms
S-033188-d1; RG 6152-d1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
References
[1]. Frederick G Hayden, et al. Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents. N Engl J Med. 2018 Sep 6;379(10):913-923. [Content Brief]
[2]. Hideyuki Ikematsu, et al. Baloxavir Marboxil for Prophylaxis against Influenza in Household Contacts. N Engl J Med. 2020 Jul 23;383(4):309-320. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Baloxavir marboxil-d1 Related Classifications
HY-109025S2 Related Classifications
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