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Cat. No.: HY-148248

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BI-2540

BI-2540, a chemical probe, is a HIV non-nucleoside reverse transcriptase (NNRT) inhibitor.

For research use only. We do not sell to patients.

CAS No.: 875145-22-5
Formula: C₂₄H₁₅ClF₅NO₅
Molecular Weight:527.82

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

BI-2540 Chemical Structure

CAS No.: 875145-22-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

BI-2540, a chemical probe, is a HIV non-nucleoside reverse transcriptase (NNRT) inhibitor^[1]^[2].

All HIV Isoforms :

In Vitro

BI-2540 (250 μM) inhibits HTop1 relaxed DDNA^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 875145-22-5
Molecular Weight 527.82
Formula C₂₄H₁₅ClF₅NO₅
SMILES

O=C(O)C1=CC=C(NC(COC2=CC=C(Cl)C=C2C(C3=CC(C(F)(F)F)=CC(F)=C3)=O)=O)C(C)=C1F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Xiao-jun Wang, et al. Practical Synthesis of A Benzophenone-Based NNRT Inhibitor of HIV-1. Org. Process Res. Dev. 2012, 16, 4, 561-566.

[2]. Madeira C. Identification of Human Topoisomerase I Poison and Catalytic Inhibitors. 2021.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

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BI-2540

All HIV Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

BI-2540 Related Classifications

HY-148248 Related Classifications