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Cat. No.: HY-19077

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BMS-180431

BMS-180431 is an inhibitor of HMG-CoA reductase (IC₅₀: 43 nM).

For research use only. We do not sell to patients.

CAS No.: 129829-03-4
Formula: C₂₃H₂₂F₂N₄O₄
Molecular Weight:456.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

BMS-180431 Chemical Structure

CAS No.: 129829-03-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

BMS-180431 is an inhibitor of HMG-CoA reductase (IC₅₀: 43 nM)^[1].

Chemical Information

CAS No. 129829-03-4
Molecular Weight 456.44
Formula C₂₃H₂₂F₂N₄O₄
SMILES

O=C(O)C[C@@H](O)C[C@@H](O)/C=C/C(C1=NN=NN1C)=C(C2=CC=C(F)C=C2)/C3=CC=C(F)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. S.Y. Sit, et al. Synthesis of tetrazol-1-yl analogs of HMG-COA reductase inhibitor BMS180431 (formerly BMY21950). Bioorganic & Medicinal Chemistry Letters. Volume 2, Issue 9, September 1992, Pages 1085-1088.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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