2. PROTAC
  3. PROTAC Linkers
  4. Boc-11-aminoundecanoic acid

Boc-11-aminoundecanoic acid is an Alkyl/ether-based PROTAC linker can be used in the synthesis of MS432 (HY-130602).

For research use only. We do not sell to patients.

Boc-11-aminoundecanoic acid Chemical Structure

Boc-11-aminoundecanoic acid Chemical Structure

CAS No. : 10436-25-6

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Based on 1 publication(s) in Google Scholar

Boc-11-aminoundecanoic acid Related Antibodies

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Description

Boc-11-aminoundecanoic acid is an Alkyl/ether-based PROTAC linker can be used in the synthesis of MS432 (HY-130602)[1].

IC50 & Target[1]

Alkyl/ether

 

In Vitro

MS432 is a first-in-class and highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Boc-11-aminoundecanoic acid Related Antibodies
Molecular Weight

301.42

Formula

C16H31NO4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CCCCCCCCCCNC(OC(C)(C)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Boc-11-aminoundecanoic acid Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Boc-11-aminoundecanoic acid10436-25-6PROTAC LinkersMS432protaclinkercancerInhibitorinhibitorinhibit

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HY-W013253
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