1. PROTAC
  2. PROTAC Linkers
  3. Boc-11-aminoundecanoic acid

Boc-11-aminoundecanoic acid 

Cat. No.: HY-W013253 Purity: ≥98.0%
COA Handling Instructions

Boc-11-aminoundecanoic acid is an Alkyl/ether-based PROTAC linker can be used in the synthesis of MS432 (HY-130602).

For research use only. We do not sell to patients.

Boc-11-aminoundecanoic acid Chemical Structure

Boc-11-aminoundecanoic acid Chemical Structure

CAS No. : 10436-25-6

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Description

Boc-11-aminoundecanoic acid is an Alkyl/ether-based PROTAC linker can be used in the synthesis of MS432 (HY-130602)[1].

IC50 & Target[1]

Alkyl/ether

 

In Vitro

MS432 is a first-in-class and highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

301.42

Formula

C16H31NO4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CCCCCCCCCCNC(OC(C)(C)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥98.0%

References
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Boc-11-aminoundecanoic acid Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Boc-11-aminoundecanoic acid
Cat. No.:
HY-W013253
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