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Cat. No.: HY-183031

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BrAA-glycine-BG-PAB-Exatecan

BrAA-glycine-BG-PAB-Exatecan (Compound LD-11) is an Drug-Linker Conjugates for ADC, consisting of Exatecan (HY-13631) and a linker. BrAA-glycine-BG-PAB-Exatecan can be conjugated with anti-ROR1 antibodies to form an ADC.

For research use only. We do not sell to patients.

CAS No.: 3059866-62-2
Formula: C₄₂H₄₁BrFN₅O₁₅
Molecular Weight:954.70

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

BrAA-glycine-BG-PAB-Exatecan Chemical Structure

CAS No.: 3059866-62-2

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Biological Activity

Description

BrAA-glycine-BG-PAB-Exatecan (Compound LD-11) is an Drug-Linker Conjugates for ADC, consisting of Exatecan (HY-13631) and a linker. BrAA-glycine-BG-PAB-Exatecan can be conjugated with anti-ROR1 antibodies to form an ADC^[1].

All Drug-Linker Conjugates for ADC Isoforms :

Chemical Information

CAS No. 3059866-62-2
Molecular Weight 954.70
Formula C₄₂H₄₁BrFN₅O₁₅
SMILES

BrCC(NCC(NC(C=C1COC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=C(C=C1)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)C(O)=O)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhu, et al. Anti-ror1 antibody and drug conjugate thereof. WO2024213040A1. WIPO (PCT). 2024-04-11.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References