BRG1-IN-1
BRG1-IN-1 (Compound 11d) is a potent inhibitor of SMARCA4/BRG1. BRG1-IN-1 shows better efficacy than PFI-3 in sensitizing GBM cells to the antiproliferative and cell death inducing effects of Temozolomide in vitro. BRG1-IN-1 enhances the inhibitor effect of Temozolomide on the growth of subcutaneous GBM tumors.
For research use only. We do not sell to patients.
- CAS No.: 2616813-99-9
- Formula: C20H19FN2O
- Molecular Weight:322.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All SWI/SNF Complex Isoforms
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Biological Activity
Chemical Information
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CAS No. 2616813-99-9
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Molecular Weight 322.38
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Formula C20H19FN2O
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SMILES
O=C(/C=C/N1[C@@H]2C[C@H](C1)N(C3=CC=C(F)C=C3)C2)C4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)