1. Protein Tyrosine Kinase/RTK
  2. c-Fms
  3. c-Fms-IN-9

c-Fms-IN-9 

Cat. No.: HY-128680
Handling Instructions

c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC50s of <0.01 μM and 0.1-1 μM, respectively.

For research use only. We do not sell to patients.

c-Fms-IN-9 Chemical Structure

c-Fms-IN-9 Chemical Structure

CAS No. : 1628574-50-4

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Description

c-Fms-IN-9 is a c-FMS inhibitor extracted from patent WO2014145023A1, Compound Example 7. c-Fms-IN-9 inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT with IC50s of <0.01 μM and 0.1-1 μM, respectively[1].

IC50 & Target

c-FMS[1]

In Vitro

c-Fms-IN-9 inhibits M-NFS-60, THP-1 and osteoclast cells proliferation with IC50s of 0.01-0.1 μM[1].

Molecular Weight

405.45

Formula

C₂₁H₂₃N₇O₂

CAS No.

1628574-50-4

SMILES

O=C1N(C2=NC(C)=C(OC3=CC(C4=CN(C)N=C4)=NC=C3)C=C2)NC(C(C)(C)C)=N1

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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