CF 1743-d7
CF 1743-d7 is the deuterium labeled Cf1743 (HY-107025). Cf1743 is a potent anti-varicella-zoster virus (VZV) bicyclic nucleoside analogue. Cf1743 has antiviral activity, with an IC50 of 3.3 μM for VZV thymidine kinase (TK).
For research use only. We do not sell to patients.
- Formula: C22H19D7N2O5
- Molecular Weight:405.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 319425-66-6
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Molecular Weight 405.50
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Formula C22H19D7N2O5
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SMILES
O[C@H]1C[C@@H](O[C@@H]1CO)N2C=C3C(OC(C4=CC=C(C=C4)CCC([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])=C3)=NC2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)