Cyclamic acid calcium
Cyclamic acid (Cyclamate) calcium is a commonly used and orally active sweetener. Cyclamic acid calcium is toxic to osteoblasts and can inhibit cell proliferation, induce apoptosis and reduce cell mineralization. Cyclamic acid calcium causes focal necrosis of bladder organs in rats in vitro, which can promote bladder cancer, but some studies have shown that low doses of Cyclamic acid calcium have no carcinogenic effect. In addition, Cyclamic acid calcium has no effect on insulin and glucagon secretion induced by arginine.
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- CAS No.: 139-06-0
- Formula: C6H13NO3S·1/2Ca
- Molecular Weight:219.02
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 139-06-0
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Molecular Weight 219.02
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Formula C6H13NO3S·1/2Ca
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SMILES
O=S(NC1CCCCC1)([O-])=O.[Ca+2].[1/2]
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Synonyms
Cyclohexylsulfamic acid calcium; Cyclamate calcium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cyclamic acid calcium Related Classifications
HY-W719824 Related Classifications
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