KPC-2-IN-2
KPC-2-IN-2 (Compound 6c) is a potent Klebsiella pneumoniae carbapenemase (KPC-2) inhibitor (Ki=0.038 μM). KPC-2-IN-2 can enhance the activity of cefotaxime in KPC-2 expressing Escherichia coli.
For research use only. We do not sell to patients.
- CAS No.: 3034185-71-9
- Formula: C12H10BN3O2S
- Molecular Weight:271.10
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
IC50: 0.038 μM (KPC-2)[1]
KPC-2-IN-2 (5 and 50 μg/mL; 24 h) treatment shows excellent tolerance in HEK-293[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:HEK-293
-
Concentration:5 and 50 μg/ml
-
Incubation Time:24 hours
-
Result:Tolerated well in the presence or absence of 30 μg/ml cefotaxime (>80% viability after 24 h).
Chemical Information
-
CAS No. 3034185-71-9
-
Molecular Weight 271.10
-
Formula C12H10BN3O2S
-
SMILES
OB(C1=CC=CC(N2C=C(N=N2)C3=CSC=C3)=C1)O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KPC-2-IN-2 Related Classifications
HY-150767 Related Classifications
Powered by Bioz