FGF-13
FGF-13 (FHF3) is an X-linked intracrine factor expressed in brain, heart, skeletal muscle and dorsal root ganglia. It functions inside cells as a modulator of voltage-gated sodium channels, notably Nav1.5 in cardiomyocytes and Nav1.6 in neurons, and has been implicated in neuronal migration during cortical development and in setting cardiac action potential duration. Loss-of-function mutations in FGF13 cause Borjeson-Forssman-Lehmann syndrome, an X-linked intellectual disability disorder, and elevated FGF13 expression has been reported in some cancers. Recombinant FGF-13 protein is used for sodium channel electrophysiology, FHF interaction studies and investigations of X-linked intellectual disability mechanisms.
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FGF-13 Recombinant Proteins (2)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
