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Cat. No.: HY-157533

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AcrB-IN-5

AcrB-IN-5 (compound 8) inhibits AcrB and blocks the efflux pump in a dose-dependent manner.

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CAS No.: 81050-84-2
Formule: C₂₁H₂₄O₇
Masse moléculaire:388.41

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

AcrB-IN-5 Chemical Structure

CAS No.: 81050-84-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

AcrB-IN-5 (compound 8) inhibits AcrB and blocks the efflux pump in a dose-dependent manner^[1].

In Vitro

AcrB-IN-5 (0-200 μM, 30 min) inhibits the efflux pump activity of AcrB, increases the H33342 accumulation by 2-fold (50 μM) and levofloxacin antibacterial activity by 4-fold (200 μM)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 81050-84-2
Masse moléculaire 388.41
Formule C₂₁H₂₄O₇
SMILES

O=C(OC1=CC(C)=C(C(OC)=O)C(O)=C1C)C2=C(C)C=C(OC)C(C)=C2OC
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Thien-Vy Phan, et al., Computational assessment and in vitro test of phytochemicals of Usnea aciculifera as potential inhibitors of Escherichia coli efflux pump AcrB, Journal of Biomolecular Structure and Dynamics

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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