Antibacterial agent 323
Antibacterial agent 323 is an antifbacterial agent with weak activity. Antibacterial agent 323 can be used for the research of bacterial nfection, such as Acinetobacter baumannii strains.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 25303-05-3
- Formule: C10H26Cl2N6
- Masse moléculaire:301.26
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
In Vitro
Antibacterial agent 323 (Compound 8f) is inactive against all tested Gram-positive and Gram-negative bacterial strains with MIC50 >128 μg/mL[1].
Antibacterial agent 323 does not effectively sensitize Gram-negative bacterial strains to Rifampicin (HY-B0272) except for mild improvement in some Acinetobacter baumannii strains[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
-
CAS No. 25303-05-3
-
Masse moléculaire 301.26
-
Formule C10H26Cl2N6
-
SMILES
N=C(NCCCCCCCCNC(N)=N)N.Cl.Cl
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
-
Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)