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Cat. No.: HY-W707498

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Baclofen-d₄-1

Baclofen-d₄-1 is the deuterium labeled Baclofen (HY-B0007). Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research.

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CAS No.: 70155-52-1
Formule: C₁₀H₈D₄ClNO₂
Masse moléculaire:217.69

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (246 KB)

Baclofen-d₄-1 Chemical Structure

CAS No.: 70155-52-1

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Activité biologique

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 70155-52-1
Unlabeled Cas 1134-47-0
Masse moléculaire 217.69
Formule C₁₀H₈D₄ClNO₂
SMILES

NC([2H])(C(C1=CC=C(C=C1)Cl)C([2H])(C(O)=O)[2H])[2H]
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.