BMS-199264
BMS-199264 is an inhibitor of F1F0 ATP hydrolase (IC50=0.5 μM) without inhibitory effect on F1F0 ATP synthase. BMS-199264 selectively inhibits ATP decline during ischemia to reduces cardiac necrosis. BMS-199264 also enhances the recovery of contractile function following reperfusion.
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- CAS No.: 675833-20-2
- Formule: C26H31ClN4O4S
- Masse moléculaire:531.07
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
Chemical Information
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CAS No. 675833-20-2
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Masse moléculaire 531.07
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Formule C26H31ClN4O4S
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SMILES
O[C@@H]1C(C)(OC2=CC=C(C=C2[C@H]1N(CC3=NC=CN3)C4=CC=C(C=C4)Cl)S(=O)(N5CCCCC5)=O)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BMS-199264 Related Classifications
HY-118960A Related Classifications
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