country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-120130

Copy Link Print Information

BMS-948

BMS-948 is a RARβ-selective transcriptional agonist with an EC₅₀ of 0.1 μM. BMS-948 is used in the research of tumor diseases, embryonic development and tissue remodeling.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 168901-49-3
Formule: C₂₄H₁₇NO₃
Masse moléculaire:367.40

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

BMS-948 Chemical Structure

CAS No.: 168901-49-3

Stock

Quantité

Amount: USD 0.00

* Veuillez sélectionner la quantité avant d'ajouter des articles.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

BMS-948 is a RARβ-selective transcriptional agonist with an EC₅₀ of 0.1 μM. BMS-948 is used in the research of tumor diseases, embryonic development and tissue remodeling^[1].

IC₅₀ & Target

RXRβ

0.1 μM (EC₅₀)

Voir tous les produits spécifiques à Isoform RAR/RXR :

In Vitro

BMS-948 acts as a fully selective agonist of RARβ in HeLa cells, with an EC₅₀ of 0.1 μM for RARβ-mediated transactivation, and exhibits extremely low activity against RARα and RARγ^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 168901-49-3
Masse moléculaire 367.40
Formule C₂₄H₁₇NO₃
SMILES

O=C(O)C1=CC=C(C=C1)NC(=O)C2=CC=C3C=CC=C(C=4C=CC=CC4)C3=C2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Nadendla E, et al. An Unexpected Mode Of Binding Defines BMS948 as A Full Retinoic Acid Receptor β (RARβ, NR1B2) Selective Agonist. PLoS One. 2015;10(5):e0123195. Published 2015 May 1. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Obtenir un devis En stock

Other size

Obtenir un devis

Amount: USD 0.00

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

Nom du produit:
Cat. No.:
Quantité:
MCE Japan Authorized Agent:

Nom du produit:
CAS No.:
Species:
Pureté:
Quantité:

BMS-948

Voir tous les produits spécifiques à Isoform RAR/RXR