c-Kit-IN-15
c-Kit-IN-15 is a c-Kit inhibitor. c-Kit-IN-15 inhibits the c-Kit signaling pathway and suppresses cancer cell proliferation. c-Kit-IN-15 can be used in research related to hepatocellular carcinoma and breast cancer.
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- Formule: C39H55NO3
- Masse moléculaire:585.86
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
c-Kit-IN-15 (Compound I9) (10 μM, 48 h) potently inhibits the proliferation of HepG-2 and MCF-7 cells, with IC50 values of 8.94 μM and 9.64 μM, respectively[1].
c-Kit-IN-15 (3-9 μM) downregulates the expression of c-Kit protein in MCF-7 cells in a concentration-dependent manner[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:human hepatocellular carcinoma HepG-2 cells, human breast cancer MCF-7 cells
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Concentration:10 μM; tested for IC50 determination
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Incubation Time:48 h
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Result:Inhibited HepG-2 cell proliferation by 55.29% and MCF-7 cell proliferation by 50.44%.
Exhibited an IC50 of 8.94 μmol/L in HepG-2 cells and 9.64 μmol/L in MCF-7 cells.
Chemical Information
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Masse moléculaire 585.86
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Formule C39H55NO3
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SMILES
O=C([C@]12CCC(C)(CC1C3=CCC4[C@]5(C=CC(C(C)(C5CC[C@]4([C@@]3(CC2)C)C)C)=O)C)C)OCCNC6=CC=CC(C)=C6
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
c-Kit-IN-15 Related Classifications
HY-181518 Related Classifications
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