CK2-IN-11
CK2-IN-11 (32) is an allosteric CK2 inhibitor, with high selectivity for CK2 with IC50 values of 19.3 nM and 15.6 nM for the CK2α2β2 and the CK2α′2β2 isoforms, respectively.
For research use only. We do not sell to patients.
- CAS No.: 2938991-22-9
- Formula: C23H22Br4Cl2N4O2
- Molecular Weight:776.97
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
15.94 μM
Compound: 2; KN2
|
Cytotoxicity against HEK293 cells assessed as reduction in cell viability incubated for 24 hrs by resazurin-based cytotoxicity assay
Cytotoxicity against HEK293 cells assessed as reduction in cell viability incubated for 24 hrs by resazurin-based cytotoxicity assay
|
[PMID: 34323071] |
| HeLa | EC50 |
6.19 μM
Compound: 2; KN2
|
Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 24 hrs by resazurin-based cytotoxicity assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 24 hrs by resazurin-based cytotoxicity assay
|
[PMID: 34323071] |
Chemical Information
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CAS No. 2938991-22-9
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Molecular Weight 776.97
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Formula C23H22Br4Cl2N4O2
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SMILES
O=C(NCCCCN1C=NC2=C(C(Br)=C(C(Br)=C21)Br)Br)CCC(NCCC3=CC=C(C(Cl)=C3)Cl)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)