Edoxaban impurity 15
Based on 1 Customer Validation
Edoxaban impurity 15 (Edoxaban N-oxide) is an impurity of Edoxaban (HY-10264). Edoxaban (DU-176b) is an orally active, highly potent, selective, and direct Factor Xa (FXa) inhibitor with Ki values of 0.561 and 2.98 nM for free human FXa and prothrombinase. Edoxaban exhibits more than 10,000-fold selectivity over other coagulation proteases. Edoxaban can be used in preventing thromboembolic disease research.
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- Pureté : 99.35%
- CAS No.: 2244103-96-4
- Formule: C24H30ClN7O5S
- Masse moléculaire:564.06
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Stockage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
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Help & FAQs
Activité biologique
Description
In Vitro
Impurities can alter the physicochemical properties of a substance and reduce product purity, yet under specific conditions, they can also be used to tune material properties.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2244103-96-4
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Appearance Solid
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Masse moléculaire 564.06
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Formule C24H30ClN7O5S
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Color Off-white to light yellow
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SMILES
CN(C)C([C@H](C[C@H]1NC(C2=NC(CC[N+](C)([O-])C3)=C3S2)=O)CC[C@@H]1NC(C(NC4=NC=C(Cl)C=C4)=O)=O)=O
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Synonyms
Edoxaban N-oxide
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvant et solubilité
In Vitro:
DMSO : 25 mg/mL (44.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (246 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Instruction de manipulation (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7729 mL | 8.8643 mL | 17.7286 mL | 44.3215 mL |
| 5 mM | 0.3546 mL | 1.7729 mL | 3.5457 mL | 8.8643 mL | |
| 10 mM | 0.1773 mL | 0.8864 mL | 1.7729 mL | 4.4322 mL | |
| 15 mM | 0.1182 mL | 0.5910 mL | 1.1819 mL | 2.9548 mL | |
| 20 mM | 0.0886 mL | 0.4432 mL | 0.8864 mL | 2.2161 mL | |
| 25 mM | 0.0709 mL | 0.3546 mL | 0.7091 mL | 1.7729 mL | |
| 30 mM | 0.0591 mL | 0.2955 mL | 0.5910 mL | 1.4774 mL | |
| 40 mM | 0.0443 mL | 0.2216 mL | 0.4432 mL | 1.1080 mL |
Edoxaban impurity 15 Related Classifications
HY-Z4525 Related Classifications
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