F1-ispinesib
F1-ispinesib is a heterobifunctional F1-autophagy degrader, composed of an RNA-binding fragment (F1) and the LC3B ligand Ispinesib (HY-50759). F1-ispinesib induces degradation of COL15A1 mRNA via an LC3B-dependent macroautophagy mechanism. F1-ispinesib inhibits cell proliferation and enhances migration of human aortic smooth muscle cells.
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- Formule: C51H52Cl3N5O4
- Masse moléculaire:905.35
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
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Help & FAQs
Activité biologique
Chemical Information
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Masse moléculaire 905.35
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Formule C51H52Cl3N5O4
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SMILES
CC1=CC=C(C=C1)C(N([C@H](C(C)C)C2=NC3=C(C(N2CC4=CC=CC=C4)=O)C=CC(Cl)=C3)CCCNC(CCC(N([C@H]5CC[C@H](C6=C5C=CC=C6)C7=CC=C(C(Cl)=C7)Cl)C)=O)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
F1-ispinesib Related Classifications
HY-180188 Related Classifications
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