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Cat. No.: HY-N11430

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F1839-I

F1839-I is a compound that can be isolated from Stachybotrys. F1839-I has weak cytotoxicity and anti-HIV activity with an IC₅₀ value of 15.6 μM.

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CAS No.: 159096-49-8
Formule: C₂₃H₃₂O₄
Masse moléculaire:372.50

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

F1839-I Chemical Structure

CAS No.: 159096-49-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

F1839-I is a compound that can be isolated from Stachybotrys. F1839-I has weak cytotoxicity and anti-HIV activity with an IC₅₀ value of 15.6 μM^[1].

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Cellular Effect

Cell Line	Type	Value	Description	References
BGC-823	IC₅₀	21.9 μM Compound: 1; F1839-I	Cytotoxicity against human BGC823 cells assessed as reduction in cell viability after 96 hrs by MTT assay Cytotoxicity against human BGC823 cells assessed as reduction in cell viability after 96 hrs by MTT assay	[PMID: 28530828]
HepG2	IC₅₀	18.4 μM Compound: 1; F1839-I	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 96 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 96 hrs by MTT assay	[PMID: 28530828]
NCI-H460	IC₅₀	15.8 μM Compound: 1; F1839-I	Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability after 96 hrs by MTT assay Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability after 96 hrs by MTT assay	[PMID: 28530828]

In Vitro

F1839-I is weakly active against the HepG2, NCI-H460 and BGC823 cells with IC₅₀ values of 18.4, 15.8 and 21.9 μM, respectively.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 159096-49-8
Masse moléculaire 372.50
Formule C₂₃H₃₂O₄
SMILES

C[C@@]12[C@@]3([C@@H](CC[C@@]1([H])C(C)([C@@H](CC2)O)C)C)OC4=C(C=O)C(C)=CC(O)=C4C3
Structure Classification
- Phenols
- Monophenols
Initial Source
- Microorganisms
Stachybotrys chartarum
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Zhao J, et al. Stachybotrysins A-G, Phenylspirodrimane Derivatives from the Fungus Stachybotrys chartarum. J Nat Prod. 2017 Jun 23;80(6):1819-1826. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références

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F1839-I

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