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Cat. No.: HY-131370B

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Intralipid 20%

Name: Intralipid 20%
Brand: MedChemExpress
SKU: HY-131370B
Price: 30.00 USD
Availability: InStock
Rating: 5 (5 reviews)

(Synonyms: 20% Fat Emulsion)

5 Cited Publications

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Based on 5 publication(s) in Google Scholar

Intralipid 20% is a safe fat emulsion, composed of soybean oil (consisting of a mixture of long-chain triglycerides (C14-24) of predominantly unsaturated fatty acids), and egg phospholipids, can be used as a nutritional supplement. Intralipid 20% effectively inhibits the opening of the mitochondrial permeability transition pore, effectively protecting the heart from ischaemia-reperfusion injury and has some potential to modulate the innate immune response.

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CAS No.: 68890-65-3

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Intralipid 20% Chemical Structure

CAS No.: 68890-65-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
- In Vivo
- Essai clinique
Chemical Information
Publications (5)
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

In Vitro

Intralipid 20% (0-0.2 mg/mL) specifically protects immune cells from paclitaxel, but has no effect on tumor cells^[1].
Intralipid 20% (0-0.2 mg/mL, 3 days) promotes polarisation of M0, M1 and M2 macrophages to an M1-like phenotype^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Intralipid (2 g/kg) does not affect phagocytosis and may promote macrophage polarization to the M1 phenotype, as observed in breast cancer tumor sections from Balb/c mice^[1].
Intralipid pretreatment promotes the accumulation of paclitaxel in tumour tissue and induces higher levels of apoptosis in tumour cells. Increased distribution of paclitaxel in mouse RES organs and enhanced inhibition of tumour growth^[1].
Intralipid (5 mL/kg) is more effective than cyclosporin-A in protecting the heart from I/R injury in SD rats, reducing the size of myocardial infarction by approximately 40%^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Transepithelial/transendothelial electrical resistance assay

Essai clinique

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 68890-65-3
Appearance Liquid (Density: 0.99 g/cm³)
Color White to off-white
SMILES

[Intralipid 20%]
Synonyms

20% Fat Emulsion
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (5)

All In Vivo Efficacy Study

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Journal Impact Factor

Nat Commun

Paraventricular hypothalamic input to anterior cingulate cortex controls food preferences in chronic visceral pain mice. [Abstract]

2025 Jul 1;16(1):5943. PMID: 40593837

Intralipid 20% purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Jul 1;16(1):5943. [Abstract]

Heatmaps of mouse location throughout the free-feeding tests, the consumption of three liquids (i.e., Sucrose, Water, and an Intralipid solution (1.5%)) and time spent in the corresponding zones in the CON and NCI mice.

Intralipid 20% purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Jul 1;16(1):5943. [Abstract]

The percentage of time spent in each food zone and percentage of each type of liquid intake.
Adv Healthc Mater

A Dual-Metabolic NIR-II Probe for In Vivo Imaging of Tumor-Infiltrating Lymphocytes. [Abstract]

2026 Mar 6:e05668. PMID: 41793059
Laser Photon Rev

2026 Feb 24.
J Biophotonics

Accelerated SPAD-Based Diffuse Optical Tomography With Data-Driven View Optimization. [Abstract]

2026 Jun;19(6):e70289. PMID: 42205110
bioRxiv

2025 Dec 23.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (276 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Jingyuan Li, et al. Intralipid, a clinically safe compound, protects the heart against ischemia-reperfusion injury more efficiently than cyclosporine-A. Anesthesiology. 2012 Oct;117(4):836-46. [Content Brief]

[2]. Yen-Ju Chen, et al. Impacts of Intralipid on Nanodrug Abraxane Therapy and on the Innate Immune System. Sci Rep. 2020 Feb 18;10(1):2838. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

Intralipid 20%

5 Cited Publications

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Activité biologique
- Description
- In Vitro
- In Vivo
- Essai clinique
Chemical Information
Publications (5)
Pureté et documentation
Références

1/16
1/16

Intralipid 20% purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Jul 1;16(1):5943. [Abstract]

Customer Validation
Heatmaps of mouse location throughout the free-feeding tests, the consumption of three liquids (i.e., Sucrose, Water, and an Intralipid solution (1.5%)) and time spent in the corresponding zones in the CON and NCI mice.
1/16

Intralipid 20% purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Jul 1;16(1):5943. [Abstract]

Customer Validation
The percentage of time spent in each food zone and percentage of each type of liquid intake.

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Intralipid 20%

Publications Citing Use of MedChemExpress (MCE) Intralipid 20%