L-731128
L-731128 is a novel alkyl citrate. L-731128 can be isolated as a minor component of Sporormiella intermedia (MF 5447, ATCC 20985) fermentations. L-731128 is a potent squalene synthase inhibitor, with an IC50 value of 767 nM.
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- CAS No.: 172722-09-7
- Formule: C25H36O7
- Masse moléculaire:448.55
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
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Help & FAQs
Activité biologique
Description
IC50 & Target
IC50: 767 nM (squalene synthase)[1]
Chemical Information
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CAS No. 172722-09-7
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Masse moléculaire 448.55
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Formule C25H36O7
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SMILES
OC(C[C@](C(O)=O)(O)[C@@H](C(O)=O)CCCCC[C@H](C)C[C@H](C)C/C=C/C1=CC=CC=C1)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
L-731128 Related Classifications
HY-123404 Related Classifications
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