country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-N11989

Copy Link Print Information

Nanangenine B

Nanangenine B is a sesquiterpenoid, which can be isolated from Aspergillus nanangensis. Nanangenine B exhibits cytotixicity in cancer cell NS-1 with an IC₅₀ of 38 μg/mL.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 1609469-72-8
Formule: C₂₁H₃₂O₆
Masse moléculaire:380.48

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Nanangenine B Chemical Structure

CAS No.: 1609469-72-8

Stock

Quantité

Amount: USD 0.00

* Veuillez sélectionner la quantité avant d'ajouter des articles.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Protocole (1)
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Nanangenine B is a sesquiterpenoid, which can be isolated from Aspergillus nanangensis. Nanangenine B exhibits cytotixicity in cancer cell NS-1 with an IC₅₀ of 38 μg/mL^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
DLD-1	IC₅₀	49 μM Compound: 2	Inhibition of TNF-alpha/IFN-gamma/IL-1beta-induced human CXCL10 (972 bp) promoter activity expressed in human DLD1 cells after 24 hrs by IRSE-driven luciferase reporter assay Inhibition of TNF-alpha/IFN-gamma/IL-1beta-induced human CXCL10 (972 bp) promoter activity expressed in human DLD1 cells after 24 hrs by IRSE-driven luciferase reporter assay	[PMID: 24792812]
DLD-1	IC₅₀	50.7 μM Compound: 2	Inhibition of Stat1 (unknown origin)-induced human CXCL10 (972 bp) promoter activity expressed in TNF-alpha/IFN-gamma/IL-1beta-stimulated human DLD1 cells after 24 hrs by luciferase reporter assay Inhibition of Stat1 (unknown origin)-induced human CXCL10 (972 bp) promoter activity expressed in TNF-alpha/IFN-gamma/IL-1beta-stimulated human DLD1 cells after 24 hrs by luciferase reporter assay	[PMID: 24792812]
DLD-1	IC₅₀	55 μM Compound: 2	Inhibition of TNF-alpha/IFN-gamma/IL-1beta-induced human CXCL10 (972 bp) promoter activity expressed in human DLD1 cells after 24 hrs by luciferase reporter assay Inhibition of TNF-alpha/IFN-gamma/IL-1beta-induced human CXCL10 (972 bp) promoter activity expressed in human DLD1 cells after 24 hrs by luciferase reporter assay	[PMID: 24792812]
DLD-1	IC₅₀	68.4 μM Compound: 2	Inhibition of NF-kappaB (unknown origin)-induced human CXCL10 (972 bp) promoter activity expressed in TNF-alpha/IFN-gamma/IL-1beta-stimulated human DLD1 cells after 24 hrs by luciferase reporter assay Inhibition of NF-kappaB (unknown origin)-induced human CXCL10 (972 bp) promoter activity expressed in TNF-alpha/IFN-gamma/IL-1beta-stimulated human DLD1 cells after 24 hrs by luciferase reporter assay	[PMID: 24792812]

Chemical Information

CAS No. 1609469-72-8
Masse moléculaire 380.48
Formule C₂₁H₃₂O₆
SMILES

C[C@]12[C@@](C(C)(CC[C@H]2O)C)([H])[C@@H](C=C3[C@@]1(C(OC3)=O)O)OC(CCCCC)=O
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
- Microorganisms
Aspergillus
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocole

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Lacey HJ, et al., Nanangenines: drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensis. Beilstein J Org Chem. 2019 Nov 5;15:2631-2643. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Obtenir un devis En stock

Other size

Obtenir un devis